BENEFITS
- Continuous granulation process
- Absence of solvents
- Small batches possible
- Low temperature operation protecting the API
- No milling necessary after extrusion
- No-upscaling of production process necessary
- Drug loading up to 50% instead of standard 20%
Typical dissolution profile
Market
Veterinary market
e.g. Medicated drinking water (anitbiotics, analgesics)
Drug precipitation leads to inaccurate drug administration (subtherapeutic concentrations) and insufficient bioavailability.
Human market
Water soluble for oral delivery, improving bioavailability.
Potential for old molecules
New application enables new stage in life cycle.
Kneading zone